Power of Attorney for Mark E. Sims

This filing is an exhibit detailing a Power of Attorney granted by Mark E. Sims, Chief Commercial Officer of Candel Therapeutics, Inc., to Paul Peter Tak and Charles Schoch. The attorneys-in-fact are authorized to execute various SEC filings on behalf of Mr. Sims, including Forms 3, 4, 5, Schedules 13D and 13G, and any necessary amendments. This delegation is to facilitate compliance with Section 16 and Regulation 13D-G of the Securities Exchange Act of 1934. The Power of Attorney remains in effect until Mr. Sims is no longer required to file such forms or until it is revoked. It also specifies that the attorneys-in-fact and the Company are not assuming Mr. Sims's compliance responsibilities and that Mr. Sims agrees to indemnify them against any losses arising from false information provided.