SEC Filing Summary

Invus Global Management, LLC, along with associated entities and individuals, has reported beneficial ownership of 5.4% of Bicycle Therapeutics plc's ordinary shares. This filing, a Schedule 13G, indicates that as of February 25, 2026, Invus Public Equities, L.P. directly held 2,719,707 American Depositary Shares (ADSs), representing 5.4% of the outstanding shares. Avicenna Life Sci Master Fund LP held an additional 429,342 ADSs, constituting 0.9%. Raymond Debbane, through various controlled entities, holds overall beneficial ownership of 3,149,049 ADSs, totaling 6.3% of the outstanding shares. The filing asserts that these securities were not acquired or held for the purpose of influencing the control of the issuer.