Perceptive Advisors LLC Increases Stake in LeonaBio, Inc. and Appoints Board Member

On May 7, 2026, Perceptive Advisors LLC filed a Schedule 13D/A regarding its holdings in LeonaBio, Inc. (ATHA). The filing reports that the reporting persons, including Joseph Edelman and Perceptive Life Sciences Master Fund, Ltd., beneficially own 1,882,370 shares of common stock, representing 19.99% of the company. This reflects a slight increase from the previously reported 1,859,322 shares. The amendment was primarily triggered by the appointment of Fred Callori, a Partner and Managing Director at Perceptive Advisors, to the Issuer's board of directors on May 5, 2026. The reporting persons' ownership is subject to a 19.99% beneficial ownership limitation regarding the exercise of certain warrants and pre-funded warrants. Currently, the limitation allows for the exercise of warrants for an aggregate of 23,048 shares. Joseph Edelman also holds stock options that are excluded from the beneficial ownership total due to a 61-day notice requirement for exercise. No other transactions were effected by the reporting persons in the past sixty days.