Amendment to Schedule 13D Filing for Athira Pharma, Inc.

This filing is an amendment to a Schedule 13D for Athira Pharma, Inc. (Ticker: ATHA), filed by Perceptive Advisors LLC and related entities. The amendment, dated December 23, 2025, reports changes in beneficial ownership. Perceptive Advisors LLC, Joseph Edelman, Perceptive Life Sciences Master Fund, Ltd., and Perceptive Xontogeny Venture Fund II, LP are the reporting persons. The total value of shares held by Perceptive Advisors LLC has increased from $3,765,863.12 to $13,758,982.80, with a corresponding increase in shares from 540,296.0 to 1,859,322.0. This brings their ownership percentage to 19.99%. The filing also details the acquisition of additional shares and warrants through a Securities Purchase Agreement, with an aggregate purchase price of $19,998,167.53. A Registration Rights Agreement has been entered into, obligating the issuer to file a resale registration statement for the acquired shares and underlying warrants.