Janus Henderson Group plc Reports 6.0% Stake in Ascendis Pharma A/S

On May 15, 2026, Janus Henderson Group plc filed a Schedule 13G/A with the SEC, reporting a 6.0% ownership stake in Ascendis Pharma A/S (ASND). The filing indicates that Janus Henderson Group plc, as the ultimate parent company of various investment advisers, beneficially owns 3,719,452 American Depositary Shares of the issuer. This position represents an increase from a previously reported 0.0% ownership level. The reporting person shares voting and dispositive power over all 3,719,452 shares with its subsidiary asset managers, which include Janus Henderson Investors US LLC and Janus Henderson Investors UK Limited, among others. The securities were acquired in the ordinary course of business and are held on behalf of various managed portfolios, including investment companies and institutional accounts. No single managed portfolio holds more than 5% of the outstanding shares. The filing was triggered by an event occurring on March 31, 2026, and serves as the ninth amendment to their ownership disclosures for this issuer.