Initial Statement of Beneficial Ownership

This filing reports the initial statement of beneficial ownership for Jean Jacques Bienaime, a director at Ascendis Pharma A/S. The filing indicates that Mr. Bienaime directly owns 0 ordinary shares. However, he also holds warrants with an exercise price of 172.35, which are convertible into 9,160 ordinary shares. These warrants vest starting June 10, 2026, with 25% vesting on that date, followed by 36 equal monthly installments. The expiration date for these warrants is June 10, 2035. The filing was made on April 1, 2026, reporting transactions as of March 23, 2026.