Initial Statement of Beneficial Ownership of Securities

This filing reports the initial statement of beneficial ownership of securities for Matthew Gregory Cohen, an insider at ARROWHEAD PHARMACEUTICALS, INC. The filing indicates that Mr. Cohen holds 0 shares of Common Stock directly following the transaction. The report was filed on June 17, 2026, pertaining to the period ending June 15, 2026. Matthew Gregory Cohen is identified as a director of the company.