Form 4 Filing for ANAPTYSBIO, INC.

Dennis Mulroy, Chief Financial Officer of ANAPTYSBIO, INC, reported transactions on December 22, 2025. Mulroy acquired 10,000 shares of common stock at $20.16 per share and disposed of 10,000 shares of common stock at $50.00 per share. These transactions were executed under a Rule 10b5-1 trading plan. Additionally, Mulroy exercised an employee stock option to acquire 10,000 shares of common stock, with a conversion or exercise price of $20.16 per share. Following these transactions, Mulroy directly holds 9,401 shares of common stock. The filing also notes that Mulroy holds additional vested options to purchase up to 339,440 shares of common stock.