Power of Attorney for Knight Jeff E.

Knight Jeff E., Chief Dev & Operating Officer of ALX Oncology Holdings Inc., has executed a Power of Attorney document. This document appoints Jason Lettmann, Harish Shantharam, and Shelly Wong as attorneys-in-fact. They are authorized to complete and execute SEC filings, including Forms 3, 4, and 5, and any amendments, related to the undersigned's securities transactions with the Company. The attorneys-in-fact are also empowered to file these forms with the SEC and other relevant entities. This Power of Attorney remains effective until Knight Jeff E. is no longer required to file these forms, or until revoked in writing. The document clarifies that the attorneys-in-fact and the Company are not assuming the undersigned's reporting responsibilities under Section 16 of the Securities Exchange Act of 1934.