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The Analysis of Spruce Street Capital LP's Holdings & P&L

Currently, Spruce Street Capital LP holds 28 types of securities in its portfolio with a total value $415.9M. In the most recent quarter, they have increased their positions in N/A (+761.1K shares, valued at $36.6M), LBRX (+1.4M shares, valued at $33.6M), DNTH (+373.3K shares, valued at $31.3M); initiated new positions in N/A (+761.1K shares, valued at $36.6M), LBRX (+1.4M shares, valued at $33.6M), DNTH (+373.3K shares, valued at $31.3M).

1M P&L

+5.8M+1.67%

3M P&L

+9.9M+2.86%

HY P&L

+105.7M+42.52%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology325.0M

93.6%

2Drug Manufacturers - Specialty & Generic11.2M

3.2%

3Medical Devices11.0M

3.2%

Top Industries by Stock Count

1Biotechnology21 stocks

91.3%

2Drug Manufacturers - Specialty & Generic1 stocks

4.3%

3Medical Devices1 stocks

4.3%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

RLMD RELMADA THERAPEUTICS INC6.3M shares53.25%2026-03-312026-05-14

KINIKSA PHARMACEUTICALS I KINIKSA PHARMACEUTICALS I761.1K sharesnew addition2026-03-312026-05-14

LBRX LB PHARMACEUTICALS INC1.4M sharesnew addition2026-03-312026-05-14

DNTH DIANTHUS THERAPEUTICS IN373.3K sharesnew addition2026-03-312026-05-14

RLAY RELAY THERAPEUTICS INC3.0M sharesnew addition2026-03-312026-05-14

ANRO ALTO NEUROSCIENCE INC1.3M sharesnew addition2026-03-312026-05-14

CNTA CENTESSA PHARMACEUTICALS489.8K sharesnew addition2026-03-312026-05-14

SVRA SAVARA INC3.4M sharesnew addition2026-03-312026-05-14

Sponsored

KALV KALVISTA PHARMACEUTICALS897.7K sharesnew addition2026-03-312026-05-14

PCVX VAXCYTE INC245.7K sharesnew addition2026-03-312026-05-14

ELVN ENLIVEN THERAPEUTICS INC329.0K sharesnew addition2026-03-312026-05-14

SURROZEN INC COM NEW SURROZEN INC COM NEW432.0K sharesnew addition2026-03-312026-05-14

ENTA ENANTA PHARMACEUTICALS I932.6K sharesnew addition2026-03-312026-05-14

ALKS ALKERMES PLC318.0K sharesnew addition2026-03-312026-05-14

CATX PERSPECTIVE THERAPEUTICS2.6M sharesnew addition2026-03-312026-05-14

NERV MINERVA NEUROSCIENC1.7M sharesnew addition2026-03-312026-05-14

Sponsored

IPSC CENTURY THERAPEUTICS4.1M sharesnew addition2026-03-312026-05-14

ALMS ALUMIS INC392.6K sharesnew addition2026-03-312026-05-14

SAB BIOTHERAPEUTICS IN SAB BIOTHERAPEUTICS IN2.2M sharesnew addition2026-03-312026-05-14

ERAS ERASCA INC422.5K sharesnew addition2026-03-312026-05-14

INHIBIKASE THERAPEUTI INHIBIKASE THERAPEUTI3.6M sharesnew addition2026-03-312026-05-14

MAZE MAZE THERAPEUTICS INC200.0K sharesnew addition2026-03-312026-05-14

ANTX AN2 THERAPEUTICS INC1.7M sharesnew addition2026-03-312026-05-14

LXEO LEXEO THERAPEUTICS INC928.6K sharesnew addition2026-03-312026-05-14

Sponsored

HELIX ACQUISITION CORP III HELIX ACQUISITION CORP III500.0K sharesnew addition2026-03-312026-05-14

ALEC ALECTOR INC2.1M sharesnew addition2026-03-312026-05-14

ATHA LEONABIO INC393.7K sharesnew addition2026-03-312026-05-14

CRVS CORVUS PHARMACEUTICALS I231.6K sharesnew addition2026-03-312026-05-14

RLMD

RELMADA THERAPEUTICS INC

53.25%

Shares6.3M

Event2026-03-31

Filed2026-05-14

KINIKSA PHARMACEUTICALS I

New

Shares761.1K

Event2026-03-31

Filed2026-05-14

LBRX

LB PHARMACEUTICALS INC

New

Shares1.4M

Event2026-03-31

Filed2026-05-14

DNTH

DIANTHUS THERAPEUTICS IN

New

Shares373.3K

Event2026-03-31

Filed2026-05-14

RLAY

RELAY THERAPEUTICS INC

New

Shares3.0M

Event2026-03-31

Filed2026-05-14

ANRO

ALTO NEUROSCIENCE INC

New

Shares1.3M

Event2026-03-31

Filed2026-05-14

CNTA

CENTESSA PHARMACEUTICALS

New

Shares489.8K

Event2026-03-31

Filed2026-05-14

SVRA

SAVARA INC

New

Shares3.4M

Event2026-03-31

Filed2026-05-14

KALV

KALVISTA PHARMACEUTICALS

New

Shares897.7K

Event2026-03-31

Filed2026-05-14

PCVX

VAXCYTE INC

New

Shares245.7K

Event2026-03-31

Filed2026-05-14

ELVN

ENLIVEN THERAPEUTICS INC

New

Shares329.0K

Event2026-03-31

Filed2026-05-14

SURROZEN INC COM NEW

New

Shares432.0K

Event2026-03-31

Filed2026-05-14

ENTA

ENANTA PHARMACEUTICALS I

New

Shares932.6K

Event2026-03-31

Filed2026-05-14

ALKS

ALKERMES PLC

New

Shares318.0K

Event2026-03-31

Filed2026-05-14

CATX

PERSPECTIVE THERAPEUTICS

New

Shares2.6M

Event2026-03-31

Filed2026-05-14

NERV

MINERVA NEUROSCIENC

New

Shares1.7M

Event2026-03-31

Filed2026-05-14

IPSC

CENTURY THERAPEUTICS

New

Shares4.1M

Event2026-03-31

Filed2026-05-14

ALMS

ALUMIS INC

New

Shares392.6K

Event2026-03-31

Filed2026-05-14

SAB BIOTHERAPEUTICS IN

New

Shares2.2M

Event2026-03-31

Filed2026-05-14

ERAS

ERASCA INC

New

Shares422.5K

Event2026-03-31

Filed2026-05-14

INHIBIKASE THERAPEUTI

New

Shares3.6M

Event2026-03-31

Filed2026-05-14

MAZE

MAZE THERAPEUTICS INC

New

Shares200.0K

Event2026-03-31

Filed2026-05-14

ANTX

AN2 THERAPEUTICS INC

New

Shares1.7M

Event2026-03-31

Filed2026-05-14

LXEO

LEXEO THERAPEUTICS INC

New

Shares928.6K

Event2026-03-31

Filed2026-05-14

HELIX ACQUISITION CORP III

New

Shares500.0K

Event2026-03-31

Filed2026-05-14

ALEC

ALECTOR INC

New

Shares2.1M

Event2026-03-31

Filed2026-05-14

ATHA

LEONABIO INC

New

Shares393.7K

Event2026-03-31

Filed2026-05-14

CRVS

CORVUS PHARMACEUTICALS I

New

Shares231.6K

Event2026-03-31

Filed2026-05-14

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available