Sponsored

The Analysis of Sofinnova Investments, Inc.'s Holdings & P&L

Currently, Sofinnova Investments, Inc. holds 61 types of securities in its portfolio with a total value $2.0B. In the most recent quarter, they have increased their positions in N/A (+456.0K shares, valued at $89.9M), RARE (+3.1M shares, valued at $64.2M), BIIB (+229.5K shares, valued at $42.1M); decreased their positions in JAZZ (-361.5K shares, valued at $68.3M), BBIO (-311.3K shares, valued at $23.1M), N/A (-62.0K shares, valued at $20.0M); initiated new positions in N/A (+456.0K shares, valued at $89.9M), BIIB (+229.5K shares, valued at $42.1M), GMAB (+752.3K shares, valued at $20.2M).

1M P&L

-79.8M-4.31%

3M P&L

-2.0M-0.11%

HY P&L

-116.2M-6.17%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology1.0B

57.9%

2Diagnostics & Research310.0M

17.2%

3Drug Manufacturers - Specialty & Generic184.4M

10.2%

Top Industries by Stock Count

1Biotechnology40 stocks

78.4%

2Medical Devices4 stocks

7.8%

3Drug Manufacturers - Specialty & Generic3 stocks

5.9%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

NTRA Natera Inc1.6M shares0.00%2026-03-312026-05-15

BMY Bristol-Myers Squibb Co2.0M shares31.44%2026-03-312026-05-15

JAZZ Jazz Pharmaceuticals PLC598.3K shares-37.67%2026-03-312026-05-15

VERA Vera Therapeutics Inc2.8M shares0.00%2026-03-312026-05-15

UTHR United Therapeutics Corp160.1K shares1.54%2026-03-312026-05-15

AstraZeneca PLC AstraZeneca PLC456.0K sharesnew addition2026-03-312026-05-15

COGT Cogent Biosciences Inc2.1M shares7.09%2026-03-312026-05-15

RARE Ultragenyx Pharmaceutical Inc3.1M shares3676.58%2026-03-312026-05-15

Sponsored

RAPP Rapport Therapeutics Inc1.9M shares0.00%2026-03-312026-05-15

INSM Insmed Inc346.1K shares120.71%2026-03-312026-05-15

ALC Alcon AG730.0K shares119.53%2026-03-312026-05-15

SUPN Supernus Pharmaceuticals954.3K shares72.54%2026-03-312026-05-15

BMRN BioMarin Pharmaceutical Inc782.0K shares12.17%2026-03-312026-05-15

BIIB Biogen Inc229.5K sharesnew addition2026-03-312026-05-15

CELC Celcuity Inc366.2K shares22.30%2026-03-312026-05-15

BIOA BioAge Labs Inc2.3M shares0.00%2026-03-312026-05-15

Sponsored

RYTM Rhythm Pharmaceuticals Inc450.1K shares65.85%2026-03-312026-05-15

AVBP Arrivent BioPharma Inc1.7M shares0.00%2026-03-312026-05-15

IDYA IDEAYA Biosciences Inc1.1M shares27.87%2026-03-312026-05-15

IMNM Immunome Inc1.7M shares5.15%2026-03-312026-05-15

Nektar Therapeutics Nektar Therapeutics509.5K shares16.17%2026-03-312026-05-15

AXSM Axsome Therapeutics Inc.212.7K shares1634.44%2026-03-312026-05-15

IMTX Immatics N.V3.6M shares5.67%2026-03-312026-05-15

BBIO BridgeBio Pharma Inc409.2K shares-43.20%2026-03-312026-05-15

Sponsored

DYN Dyne Therapeutics Inc1.6M shares-27.52%2026-03-312026-05-15

Inhibrx Biosciences Inc Inhibrx Biosciences Inc406.0K shares-10.70%2026-03-312026-05-15

DXCM Dexcom Inc393.6K shares4.06%2026-03-312026-05-15

PHVS Pharvaris N V818.3K shares9.82%2026-03-312026-05-15

Praxis Precision Medicines Inc Praxis Precision Medicines Inc63.7K shares-49.35%2026-03-312026-05-15

GMAB Genmab A/S752.3K sharesnew addition2026-03-312026-05-15

RCUS Arcus Biosciences Inc923.1K shares-15.83%2026-03-312026-05-15

XENE Xenon Pharmaceuticals Inc305.2K shares409.54%2026-03-312026-05-15

Sponsored

SYK Stryker Corporation44.5K sharesnew addition2026-03-312026-05-15

ANAB AnaptysBio Inc248.3K shares-13.71%2026-03-312026-05-15

ROIV Roivant Sciences Ltd478.0K shares-34.93%2026-03-312026-05-15

EWTX Edgewise Therapeutics Inc386.5K shares-11.72%2026-03-312026-05-15

CMPX Compass Therapeutics Inc2.1M shares-38.90%2026-03-312026-05-15

ORIC Oric Pharmaceuticals Inc679.6K sharesnew addition2026-03-312026-05-15

TNGX Tango Therapeutics Inc395.1K sharesnew addition2026-03-312026-05-15

TYRA Tyra Biosciences Inc204.0K sharesnew addition2026-03-312026-05-15

Sponsored

AXGN AxoGen Inc210.7K sharesnew addition2026-03-312026-05-15

Definium Therapeutics Inc Definium Therapeutics Inc344.2K sharesnew addition2026-03-312026-05-15

CYTK Cytokinetics Inc91.8K sharesnew addition2026-03-312026-05-15

IRON Disc Medicine Inc78.3K shares-29.45%2026-03-312026-05-15

Veradermics Inc Veradermics Inc73.3K sharesnew addition2026-03-312026-05-15

HRMY Harmony Biosciences Hldgs Inc152.7K sharesnew addition2026-03-312026-05-15

PCVX Vaxcyte Inc50.6K sharesnew addition2026-03-312026-05-15

MIRM Mirum Pharmaceuticals Inc27.6K shares19.44%2026-03-312026-05-15

Sponsored

NXTC Nextcure Inc222.7K shares0.00%2026-03-312026-05-15

SVRA Savara Inc364.8K shares19.68%2026-03-312026-05-15

ESTA Establishment Labs Hldgs Inc33.9K shares19.62%2026-03-312026-05-15

ACAD Acadia Pharmaceuticals Inc78.6K shares19.80%2026-03-312026-05-15

Tenax Therapeutics Inc Tenax Therapeutics Inc104.4K sharesnew addition2026-03-312026-05-15

JBIO Jade Biosciences Inc107.4K shares0.00%2026-03-312026-05-15

WVE Wave Life Sciences Ltd189.3K shares19.64%2026-03-312026-05-15

SEPN Septerna Inc47.5K sharesnew addition2026-03-312026-05-15

Sponsored

Onkure Therapeutics Inc Onkure Therapeutics Inc141.7K sharesnew addition2026-03-312026-05-15

BOLT Bolt Biotherapeutics Inc137.7K shares0.00%2026-03-312026-05-15

Soleno Therapeutics Inc Soleno Therapeutics Inc14.7K shares18.33%2026-03-312026-05-15

IMA ImageneBio Inc31.9K shares0.00%2026-03-312026-05-15

Zymeworks Inc Zymeworks Inc1.6K sharesnew addition2026-03-312026-05-15

NTRA

Natera Inc

0.00%

Shares1.6M

Event2026-03-31

Filed2026-05-15

BMY

Bristol-Myers Squibb Co

31.44%

Shares2.0M

Event2026-03-31

Filed2026-05-15

JAZZ

Jazz Pharmaceuticals PLC

-37.67%

Shares598.3K

Event2026-03-31

Filed2026-05-15

VERA

Vera Therapeutics Inc

0.00%

Shares2.8M

Event2026-03-31

Filed2026-05-15

UTHR

United Therapeutics Corp

1.54%

Shares160.1K

Event2026-03-31

Filed2026-05-15

AstraZeneca PLC

New

Shares456.0K

Event2026-03-31

Filed2026-05-15

COGT

Cogent Biosciences Inc

7.09%

Shares2.1M

Event2026-03-31

Filed2026-05-15

RARE

Ultragenyx Pharmaceutical Inc

3676.58%

Shares3.1M

Event2026-03-31

Filed2026-05-15

RAPP

Rapport Therapeutics Inc

0.00%

Shares1.9M

Event2026-03-31

Filed2026-05-15

INSM

Insmed Inc

120.71%

Shares346.1K

Event2026-03-31

Filed2026-05-15

ALC

Alcon AG

119.53%

Shares730.0K

Event2026-03-31

Filed2026-05-15

SUPN

Supernus Pharmaceuticals

72.54%

Shares954.3K

Event2026-03-31

Filed2026-05-15

BMRN

BioMarin Pharmaceutical Inc

12.17%

Shares782.0K

Event2026-03-31

Filed2026-05-15

BIIB

Biogen Inc

New

Shares229.5K

Event2026-03-31

Filed2026-05-15

CELC

Celcuity Inc

22.30%

Shares366.2K

Event2026-03-31

Filed2026-05-15

BIOA

BioAge Labs Inc

0.00%

Shares2.3M

Event2026-03-31

Filed2026-05-15

RYTM

Rhythm Pharmaceuticals Inc

65.85%

Shares450.1K

Event2026-03-31

Filed2026-05-15

AVBP

Arrivent BioPharma Inc

0.00%

Shares1.7M

Event2026-03-31

Filed2026-05-15

IDYA

IDEAYA Biosciences Inc

27.87%

Shares1.1M

Event2026-03-31

Filed2026-05-15

IMNM

Immunome Inc

5.15%

Shares1.7M

Event2026-03-31

Filed2026-05-15

Nektar Therapeutics

16.17%

Shares509.5K

Event2026-03-31

Filed2026-05-15

AXSM

Axsome Therapeutics Inc.

1634.44%

Shares212.7K

Event2026-03-31

Filed2026-05-15

IMTX

Immatics N.V

5.67%

Shares3.6M

Event2026-03-31

Filed2026-05-15

BBIO

BridgeBio Pharma Inc

-43.20%

Shares409.2K

Event2026-03-31

Filed2026-05-15

DYN

Dyne Therapeutics Inc

-27.52%

Shares1.6M

Event2026-03-31

Filed2026-05-15

Inhibrx Biosciences Inc

-10.70%

Shares406.0K

Event2026-03-31

Filed2026-05-15

DXCM

Dexcom Inc

4.06%

Shares393.6K

Event2026-03-31

Filed2026-05-15

PHVS

Pharvaris N V

9.82%

Shares818.3K

Event2026-03-31

Filed2026-05-15

Praxis Precision Medicines Inc

-49.35%

Shares63.7K

Event2026-03-31

Filed2026-05-15

GMAB

Genmab A/S

New

Shares752.3K

Event2026-03-31

Filed2026-05-15

RCUS

Arcus Biosciences Inc

-15.83%

Shares923.1K

Event2026-03-31

Filed2026-05-15

XENE

Xenon Pharmaceuticals Inc

409.54%

Shares305.2K

Event2026-03-31

Filed2026-05-15

SYK

Stryker Corporation

New

Shares44.5K

Event2026-03-31

Filed2026-05-15

ANAB

AnaptysBio Inc

-13.71%

Shares248.3K

Event2026-03-31

Filed2026-05-15

ROIV

Roivant Sciences Ltd

-34.93%

Shares478.0K

Event2026-03-31

Filed2026-05-15

EWTX

Edgewise Therapeutics Inc

-11.72%

Shares386.5K

Event2026-03-31

Filed2026-05-15

CMPX

Compass Therapeutics Inc

-38.90%

Shares2.1M

Event2026-03-31

Filed2026-05-15

ORIC

Oric Pharmaceuticals Inc

New

Shares679.6K

Event2026-03-31

Filed2026-05-15

TNGX

Tango Therapeutics Inc

New

Shares395.1K

Event2026-03-31

Filed2026-05-15

TYRA

Tyra Biosciences Inc

New

Shares204.0K

Event2026-03-31

Filed2026-05-15

AXGN

AxoGen Inc

New

Shares210.7K

Event2026-03-31

Filed2026-05-15

Definium Therapeutics Inc

New

Shares344.2K

Event2026-03-31

Filed2026-05-15

CYTK

Cytokinetics Inc

New

Shares91.8K

Event2026-03-31

Filed2026-05-15

IRON

Disc Medicine Inc

-29.45%

Shares78.3K

Event2026-03-31

Filed2026-05-15

Veradermics Inc

New

Shares73.3K

Event2026-03-31

Filed2026-05-15

HRMY

Harmony Biosciences Hldgs Inc

New

Shares152.7K

Event2026-03-31

Filed2026-05-15

PCVX

Vaxcyte Inc

New

Shares50.6K

Event2026-03-31

Filed2026-05-15

MIRM

Mirum Pharmaceuticals Inc

19.44%

Shares27.6K

Event2026-03-31

Filed2026-05-15

NXTC

Nextcure Inc

0.00%

Shares222.7K

Event2026-03-31

Filed2026-05-15

SVRA

Savara Inc

19.68%

Shares364.8K

Event2026-03-31

Filed2026-05-15

ESTA

Establishment Labs Hldgs Inc

19.62%

Shares33.9K

Event2026-03-31

Filed2026-05-15

ACAD

Acadia Pharmaceuticals Inc

19.80%

Shares78.6K

Event2026-03-31

Filed2026-05-15

Tenax Therapeutics Inc

New

Shares104.4K

Event2026-03-31

Filed2026-05-15

JBIO

Jade Biosciences Inc

0.00%

Shares107.4K

Event2026-03-31

Filed2026-05-15

WVE

Wave Life Sciences Ltd

19.64%

Shares189.3K

Event2026-03-31

Filed2026-05-15

SEPN

Septerna Inc

New

Shares47.5K

Event2026-03-31

Filed2026-05-15

Onkure Therapeutics Inc

New

Shares141.7K

Event2026-03-31

Filed2026-05-15

BOLT

Bolt Biotherapeutics Inc

0.00%

Shares137.7K

Event2026-03-31

Filed2026-05-15

Soleno Therapeutics Inc

18.33%

Shares14.7K

Event2026-03-31

Filed2026-05-15

IMA

ImageneBio Inc

0.00%

Shares31.9K

Event2026-03-31

Filed2026-05-15

Zymeworks Inc

New

Shares1.6K

Event2026-03-31

Filed2026-05-15

Call Option Holdings

PFE Call CallPfizer Inc800.0K sharesnew addition2026-03-312026-05-15

REPL Call CallReplimune Group Inc1.0M sharesnew addition2026-03-312026-05-15

RARE Call CallUltragenyx Pharmaceutical Inc350.0K sharesnew addition2026-03-312026-05-15

CMPX Call CallCompass Therapeutics Inc500.0K sharesnew addition2026-03-312026-05-15

PFE Call

Pfizer Inc

New

Shares800.0K

Event2026-03-31

Filed2026-05-15

REPL Call

Replimune Group Inc

New

Shares1.0M

Event2026-03-31

Filed2026-05-15

RARE Call

Ultragenyx Pharmaceutical Inc

New

Shares350.0K

Event2026-03-31

Filed2026-05-15

CMPX Call

Compass Therapeutics Inc

New

Shares500.0K

Event2026-03-31

Filed2026-05-15

Put Option Holdings

IWM Put PutiShares TR600.0K sharesnew addition2026-03-312026-05-15

XBI Put PutSPDR Series Trust1.1M sharesnew addition2026-03-312026-05-15

Invesco QQQ TR Put PutInvesco QQQ TR150.0K sharesnew addition2026-03-312026-05-15

IBB Put PutiShares TR475.0K sharesnew addition2026-03-312026-05-15

UTHR Put PutUnited Therapeutics Corp80.3K sharesnew addition2026-03-312026-05-15

CELC Put PutCelcuity Inc300.0K sharesnew addition2026-03-312026-05-15

AXSM Put PutAxsome Therapeutics Inc.200.0K sharesnew addition2026-03-312026-05-15

LQDA Put PutLiquidia Corporation500.0K sharesnew addition2026-03-312026-05-15

EXEL Put PutExelixis Inc251.5K sharesnew addition2026-03-312026-05-15

IWM Put

iShares TR

New

Shares600.0K

Event2026-03-31

Filed2026-05-15

XBI Put

SPDR Series Trust

New

Shares1.1M

Event2026-03-31

Filed2026-05-15

Invesco QQQ TR Put

Invesco QQQ TR

New

Shares150.0K

Event2026-03-31

Filed2026-05-15

IBB Put

iShares TR

New

Shares475.0K

Event2026-03-31

Filed2026-05-15

UTHR Put

United Therapeutics Corp

New

Shares80.3K

Event2026-03-31

Filed2026-05-15

CELC Put

Celcuity Inc

New

Shares300.0K

Event2026-03-31

Filed2026-05-15

AXSM Put

Axsome Therapeutics Inc.

New

Shares200.0K

Event2026-03-31

Filed2026-05-15

LQDA Put

Liquidia Corporation

New

Shares500.0K

Event2026-03-31

Filed2026-05-15

EXEL Put

Exelixis Inc

New

Shares251.5K

Event2026-03-31

Filed2026-05-15