The Analysis of Opaleye Management Inc.'s Holdings
Currently, Opaleye Management Inc. holds 44 types of securities in its portfolio with a total value $702.7M. In the most recent quarter, they have increased their positions in RZLT (+4.0M shares, valued at $37.7M), APGE (+363.3K shares, valued at $14.4M), ALKS (+450.0K shares, valued at $13.5M); decreased their positions in CDXS (-3.8M shares, valued at $9.3M), ARVN (-692.2K shares, valued at $5.9M), IMNM (-344.6K shares, valued at $4.0M); initiated new positions in APGE (+363.3K shares, valued at $14.4M), ALKS (+450.0K shares, valued at $13.5M), KPTI (+1.6M shares, valued at $8.7M). Stock Holdings
TickerCompany NameSharesShares âŗ%Event DateReport DateHistory
HROW HARROW HEALTH INC3.9M shares0.00%2025-09-302025-11-14
ETON ETON PHARMACEUTICALS INC2.9M shares0.00%2025-09-302025-11-14 LQDA LIQUIDIA CORPORATION2.6M shares5.66%2025-09-302025-11-14 RYTM RHYTHM PHARMACEUTICALS INC461.7K shares-2.80%2025-09-302025-11-14 IMNM IMMUNOME INC3.2M shares-9.76%2025-09-302025-11-14 SNWV SANUWAVE HEALTH INC980.0K shares0.00%2025-09-302025-11-14 TGTX TG THERAPEUTICS INC535.0K shares0.00%2025-09-302025-11-14 OCUL OCULAR THERAPEUTIX INC1.6M shares0.00%2025-09-302025-11-14 CDXS CODEXIS INC9.0M shares-29.75%2025-12-032025-12-05 CGON CG ONCOLOGY INC410.0K shares54.14%2025-09-302025-11-14 STOK STOKE THERAPEUTICS INC682.0K shares21.33%2025-09-302025-11-14 APGE APOGEE THERAPEUTICS INC363.3K sharesnew addition2025-09-302025-11-14 ALKS ALKERMES PLC450.0K sharesnew addition2025-09-302025-11-14 IRON DISC MEDICINE INC193.8K shares3.95%2025-09-302025-11-14 SRPT SAREPTA THERAPEUTICS INC585.0K shares17.00%2025-09-302025-11-14 LRMR LARIMAR THERAPEUTICS INC3.7M shares-9.47%2025-09-302025-11-14 XOMA XOMA CORP DEL255.1K shares0.00%2025-09-302025-11-14 RZLT REZOLUTE INC4.9M shares443.80%2025-12-122025-12-19 KPTI 1.6M sharesnew addition2025-10-102025-10-17 ARVN ARVINAS INC987.8K shares-41.20%2025-09-302025-11-14 EWTX EDGEWISE THERAPEUTICS INC500.0K shares2.04%2025-09-302025-11-14 ANNX ANNEXON INC2.6M sharesnew addition2025-09-302025-11-14 GOSS GOSSAMER BIO INC2.7M shares-23.13%2025-09-302025-11-14 PTGX PROTAGONIST THERAPEUTICS INC105.0K shares0.00%2025-09-302025-11-14 DERM JOURNEY MEDICAL CORP971.1K shares922.17%2025-09-302025-11-14 SLGL SOL GEL TECHNOLOGIES204.8K sharesnew addition2025-09-302025-11-14 PLX PROTALIX BIOTHERAPEUTICS INC2.6M sharesnew addition2025-09-302025-11-14 TMCI TREACE MEDICAL CONCEPTS INC702.2K sharesnew addition2025-09-302025-11-14 RVMD REVOLUTION MEDICINES INC100.0K shares-4.76%2025-09-302025-11-14 MBX MBX BIOSCIENCES INC253.0K shares5.72%2025-09-302025-11-14 TRVI TREVI THERAPEUTICS INC390.0K shares0.00%2025-09-302025-11-14 ADCT ADC Therapeutics SA682.5K sharesnew addition2025-09-302025-11-14 ALMS ALUMIS INC665.0K shares-14.19%2025-09-302025-11-14 CABA CABALETTA BIO INC808.9K sharesnew addition2025-09-302025-11-14 IRD OPUS GENETICS INC1.1M shares-9.84%2025-09-302025-11-14 ZYME ZYMEWORKS INC100.0K shares-52.38%2025-09-302025-11-14 SYRE SPYRE THERAPEUTICS INC65.0K sharesnew addition2025-09-302025-11-14 RIGL RIGEL PHARMACEUTICALS37.8K sharesnew addition2025-09-302025-11-14 ACOG ALPHA COGNITION INC115.1K sharesnew addition2025-09-302025-11-14 ZNTL ZENTALIS PHARMACEUTICALS INC316.6K shares-83.55%2025-09-302025-11-14 PEPG PEPGEN INC75.0K shares-68.75%2025-09-302025-11-14 IBIO IBIO INC375.0K shares0.00%2025-09-302025-11-14 ADGM ADAGIO MED HLDGS INC110.6K shares0.00%2025-09-302025-11-14 Call Option Holdings
No call option holdings data available
Put Option Holdings
No put option holdings data available