The Analysis of ARCH Venture Management, LLC's Holdings & P&L

Currently, ARCH Venture Management, LLC holds 10 types of securities in its portfolio with a total value $677.1M. In the most recent quarter, they have increased their positions in GENB (+1.9M shares, valued at $24.3M), LYEL (+488.1K shares, valued at $9.8M); decreased their positions in ERAS (-4.0M shares, valued at $64.1M), TXG (-519.7K shares, valued at $11.0M); initiated new positions in GENB (+1.9M shares, valued at $24.3M).

1M P&L

+71.5M+10.44%

3M P&L

+84.8M+12.64%

HY P&L

+24.9M+3.41%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology648.2M

95.7%

2N/A24.3M

3.6%

3Health Information Services4.6M

0.7%

Top Industries by Stock Count

1Biotechnology8 stocks

80.0%

2Health Information Services1 stocks

10.0%

3N/A1 stocks

10.0%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

MAZE MAZE THERAPEUTICS INC4.1M shares0.00%2026-03-312026-05-15

RAPP RAPPORT THERAPEUTICS INC3.7M shares0.00%2026-03-312026-05-15

VIR VIR BIOTECHNOLOGY INC12.9M shares0.00%2026-03-312026-05-15

ERAS ERASCA INC7.1M shares-35.86%2026-03-312026-05-15

BEAM BEAM THERAPEUTICS INC4.5M shares0.00%2026-03-312026-05-15

LYEL LYELL IMMUNOPHARMA INC3.2M shares17.69%2026-03-312026-05-15

GENB GENERATE BIOMEDICINES INC1.9M sharesnew addition2026-03-312026-05-15

TXG 10X GENOMICS INC217.8K shares-70.46%2026-03-312026-05-15

Sponsored

GOSS GOSSAMER BIO INC8.1M shares0.00%2026-03-312026-05-15

QTTB Q32 BIO INC320.5K shares0.00%2026-03-312026-05-15

MAZE

MAZE THERAPEUTICS INC

0.00%

Shares4.1M

Event2026-03-31

Filed2026-05-15

RAPP

RAPPORT THERAPEUTICS INC

0.00%

Shares3.7M

Event2026-03-31

Filed2026-05-15

VIR

VIR BIOTECHNOLOGY INC

0.00%

Shares12.9M

Event2026-03-31

Filed2026-05-15

ERAS

ERASCA INC

-35.86%

Shares7.1M

Event2026-03-31

Filed2026-05-15

BEAM

BEAM THERAPEUTICS INC

0.00%

Shares4.5M

Event2026-03-31

Filed2026-05-15

LYEL

LYELL IMMUNOPHARMA INC

17.69%

Shares3.2M

Event2026-03-31

Filed2026-05-15

GENB

GENERATE BIOMEDICINES INC

New

Shares1.9M

Event2026-03-31

Filed2026-05-15

TXG

10X GENOMICS INC

-70.46%

Shares217.8K

Event2026-03-31

Filed2026-05-15

GOSS

GOSSAMER BIO INC

0.00%

Shares8.1M

Event2026-03-31

Filed2026-05-15

QTTB

Q32 BIO INC

0.00%

Shares320.5K

Event2026-03-31

Filed2026-05-15

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available