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The Analysis of 5AM Venture Management, LLC's Holdings & P&L

Currently, 5AM Venture Management, LLC holds 20 types of securities in its portfolio with a total value $360.2M. In the most recent quarter, they have increased their positions in ALXO (+3.1M shares, valued at $6.1M), RLYB (+291.8K shares, valued at $2.6M); decreased their positions in ERAS (-1.9M shares, valued at $31.1M); initiated new positions in ALXO (+3.1M shares, valued at $6.1M), RLYB (+291.8K shares, valued at $2.6M).

1M P&L

+46.0M+14.10%

3M P&L

-20.6M-5.23%

HY P&L

+82.2M+28.31%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology360.2M

100.0%

Top Industries by Stock Count

1Biotechnology20 stocks

100.0%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

ERAS ERASCA INC3.5M shares-35.51%2026-03-312026-05-15

TRDA ENTRADA THERAPEUTICS INC4.1M shares0.00%2026-03-312026-05-15

TYRA TYRA BIOSCIENCES INC1.0M shares0.00%2026-03-312026-05-15

CAMP CAMP4 THERAPEUTICS CORP5.9M shares0.00%2026-03-312026-05-15

CNTA CENTESSA PHARMACEUTICALS PLC580.9K shares0.00%2026-03-312026-05-15

PHVS PHARVARIS N V797.6K shares0.00%2026-03-312026-05-15

MPLT MAPLIGHT THERAPEUTICS INC950.0K shares0.00%2026-03-312026-05-15

TECX TECTONIC THERAPEUTIC INC606.7K shares0.00%2026-03-312026-05-15

Sponsored

CLDX CELLDEX THERAPEUTICS INC NEW497.3K shares0.00%2026-03-312026-05-15

ARTV ARTIVA BIOTHERAPEUTICS INC2.4M shares0.00%2026-03-312026-05-15

EYPT EYEPOINT INC1.1M shares0.00%2026-03-312026-05-15

SRZN SURROZEN INC387.5K shares0.00%2026-03-312026-05-15

ZNTL ZENTALIS PHARMACEUTICALS INC3.9M shares0.00%2026-03-312026-05-15

GHRS GH RESEARCH PLC572.7K shares0.00%2026-03-312026-05-15

TARA PROTARA THERAPEUTICS INC1.4M shares0.00%2026-03-312026-05-15

BHVN BIOHAVEN LTD739.0K shares0.00%2026-03-312026-05-15

Sponsored

ALXO ALX ONCOLOGY HLDGS INC3.1M sharesnew addition2026-03-312026-05-15

SKYE SKYE BIOSCIENCE INC9.7M shares0.00%2026-03-312026-05-15

RLYB RALLYBIO CORP291.8K sharesnew addition2026-03-312026-05-15

SLN SILENCE THERAPEUTICS PLC476.2K shares0.00%2026-03-312026-05-15

ERAS

ERASCA INC

-35.51%

Shares3.5M

Event2026-03-31

Filed2026-05-15

TRDA

ENTRADA THERAPEUTICS INC

0.00%

Shares4.1M

Event2026-03-31

Filed2026-05-15

TYRA

TYRA BIOSCIENCES INC

0.00%

Shares1.0M

Event2026-03-31

Filed2026-05-15

CAMP

CAMP4 THERAPEUTICS CORP

0.00%

Shares5.9M

Event2026-03-31

Filed2026-05-15

CNTA

CENTESSA PHARMACEUTICALS PLC

0.00%

Shares580.9K

Event2026-03-31

Filed2026-05-15

PHVS

PHARVARIS N V

0.00%

Shares797.6K

Event2026-03-31

Filed2026-05-15

MPLT

MAPLIGHT THERAPEUTICS INC

0.00%

Shares950.0K

Event2026-03-31

Filed2026-05-15

TECX

TECTONIC THERAPEUTIC INC

0.00%

Shares606.7K

Event2026-03-31

Filed2026-05-15

CLDX

CELLDEX THERAPEUTICS INC NEW

0.00%

Shares497.3K

Event2026-03-31

Filed2026-05-15

ARTV

ARTIVA BIOTHERAPEUTICS INC

0.00%

Shares2.4M

Event2026-03-31

Filed2026-05-15

EYPT

EYEPOINT INC

0.00%

Shares1.1M

Event2026-03-31

Filed2026-05-15

SRZN

SURROZEN INC

0.00%

Shares387.5K

Event2026-03-31

Filed2026-05-15

ZNTL

ZENTALIS PHARMACEUTICALS INC

0.00%

Shares3.9M

Event2026-03-31

Filed2026-05-15

GHRS

GH RESEARCH PLC

0.00%

Shares572.7K

Event2026-03-31

Filed2026-05-15

TARA

PROTARA THERAPEUTICS INC

0.00%

Shares1.4M

Event2026-03-31

Filed2026-05-15

BHVN

BIOHAVEN LTD

0.00%

Shares739.0K

Event2026-03-31

Filed2026-05-15

ALXO

ALX ONCOLOGY HLDGS INC

New

Shares3.1M

Event2026-03-31

Filed2026-05-15

SKYE

SKYE BIOSCIENCE INC

0.00%

Shares9.7M

Event2026-03-31

Filed2026-05-15

RLYB

RALLYBIO CORP

New

Shares291.8K

Event2026-03-31

Filed2026-05-15

SLN

SILENCE THERAPEUTICS PLC

0.00%

Shares476.2K

Event2026-03-31

Filed2026-05-15

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available