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The Analysis of 5AM Venture Management, LLC's Holdings & P&L

Currently, 5AM Venture Management, LLC holds 21 types of securities in its portfolio with a total value $318.1M. In the most recent quarter, they have increased their positions in N/A (+950.0K shares, valued at $16.7M), ZNTL (+3.5M shares, valued at $4.7M), TARA (+569.8K shares, valued at $3.0M); decreased their positions in CNTA (-100.0K shares, valued at $2.5M), TRDA (-200.0K shares, valued at $2.1M); initiated new positions in N/A (+950.0K shares, valued at $16.7M).

1M P&L

+76.8M+21.12%

3M P&L

+119.5M+37.26%

HY P&L

+225.2M+104.74%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology277.1M

100.0%

Top Industries by Stock Count

1Biotechnology17 stocks

100.0%

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Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

TRDA ENTRADA THERAPEUTICS INC4.1M shares-4.70%2025-12-312026-02-17

CAMP CAMP4 THERAPEUTICS CORP5.9M shares0.00%2025-12-312026-02-17

TYRA TYRA BIOSCIENCES INC1.0M shares9.58%2025-12-312026-02-17

VRDN VIRIDIAN THERAPEUTICS INC736.6K shares0.00%2025-12-312026-02-17

PHVS PHARVARIS N V797.6K shares0.00%2025-12-312026-02-17

ERAS ERASCA INC5.4M shares0.00%2025-12-312026-02-17

EYPT EYEPOINT INC1.1M shares0.00%2025-12-312026-02-17

MAPLIGHT THERAPEUTICS INC MAPLIGHT THERAPEUTICS INC950.0K sharesnew addition2025-12-312026-02-17

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CNTA CENTESSA PHARMACEUTICALS PLC580.9K shares-14.69%2025-12-312026-02-17

CLDX CELLDEX THERAPEUTICS INC NEW497.3K shares0.00%2025-12-312026-02-17

TECX TECTONIC THERAPEUTIC INC606.7K shares18.57%2025-12-312026-02-17

ELVN ENLIVEN THERAPEUTICS INC772.5K shares0.00%2025-12-312026-02-17

ARTV ARTIVA BIOTHERAPEUTICS INC2.4M shares0.00%2025-12-312026-02-17

SURROZEN INC SURROZEN INC387.5K shares25.00%2025-12-312026-02-17

BIOHAVEN LTD BIOHAVEN LTD739.0K shares54.28%2025-12-312026-02-17

TARA PROTARA THERAPEUTICS INC1.4M shares71.22%2025-12-312026-02-17

Sponsored

GHRS GH RESEARCH PLC572.7K shares0.00%2025-12-312026-02-17

SKYE BIOSCIENCE INC SKYE BIOSCIENCE INC9.7M shares0.00%2025-12-312026-02-17

ZNTL ZENTALIS PHARMACEUTICALS INC3.9M shares705.70%2025-12-312026-02-17

SLN SILENCE THERAPEUTICS PLC476.2K shares0.00%2025-12-312026-02-17

RLYB RALLYBIO CORP3.6M shares0.00%2025-12-312026-02-17

TRDA

ENTRADA THERAPEUTICS INC

-4.70%

Shares4.1M

Event2025-12-31

Filed2026-02-17

CAMP

CAMP4 THERAPEUTICS CORP

0.00%

Shares5.9M

Event2025-12-31

Filed2026-02-17

TYRA

TYRA BIOSCIENCES INC

9.58%

Shares1.0M

Event2025-12-31

Filed2026-02-17

VRDN

VIRIDIAN THERAPEUTICS INC

0.00%

Shares736.6K

Event2025-12-31

Filed2026-02-17

PHVS

PHARVARIS N V

0.00%

Shares797.6K

Event2025-12-31

Filed2026-02-17

ERAS

ERASCA INC

0.00%

Shares5.4M

Event2025-12-31

Filed2026-02-17

EYPT

EYEPOINT INC

0.00%

Shares1.1M

Event2025-12-31

Filed2026-02-17

MAPLIGHT THERAPEUTICS INC

New

Shares950.0K

Event2025-12-31

Filed2026-02-17

CNTA

CENTESSA PHARMACEUTICALS PLC

-14.69%

Shares580.9K

Event2025-12-31

Filed2026-02-17

CLDX

CELLDEX THERAPEUTICS INC NEW

0.00%

Shares497.3K

Event2025-12-31

Filed2026-02-17

TECX

TECTONIC THERAPEUTIC INC

18.57%

Shares606.7K

Event2025-12-31

Filed2026-02-17

ELVN

ENLIVEN THERAPEUTICS INC

0.00%

Shares772.5K

Event2025-12-31

Filed2026-02-17

ARTV

ARTIVA BIOTHERAPEUTICS INC

0.00%

Shares2.4M

Event2025-12-31

Filed2026-02-17

SURROZEN INC

25.00%

Shares387.5K

Event2025-12-31

Filed2026-02-17

BIOHAVEN LTD

54.28%

Shares739.0K

Event2025-12-31

Filed2026-02-17

TARA

PROTARA THERAPEUTICS INC

71.22%

Shares1.4M

Event2025-12-31

Filed2026-02-17

GHRS

GH RESEARCH PLC

0.00%

Shares572.7K

Event2025-12-31

Filed2026-02-17

SKYE BIOSCIENCE INC

0.00%

Shares9.7M

Event2025-12-31

Filed2026-02-17

ZNTL

ZENTALIS PHARMACEUTICALS INC

705.70%

Shares3.9M

Event2025-12-31

Filed2026-02-17

SLN

SILENCE THERAPEUTICS PLC

0.00%

Shares476.2K

Event2025-12-31

Filed2026-02-17

RLYB

RALLYBIO CORP

0.00%

Shares3.6M

Event2025-12-31

Filed2026-02-17

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available